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Toxic metals are metals that form poisonous soluble compounds and have no biological role, for example are not essential minerals, or are in the wrong form. Often heavy metals are thought as synonymous, but lighter metals also have toxicity, as exemplified by beryllium, and not all heavy metals are particularly toxic and some are even essential (such as iron). The definition may also include trace elements when considered in abnormally high, toxic doses. A difference is that there's no beneficial dose for a toxic metal with no biological role.
   Toxic metals sometimes imitate the action of an essential element in the body, interfering with the metabolic process to cause illness. Many metals, particularly heavy metals are toxic, but some heavy metals are essential, have a low toxicity, and bismuth is even non-toxic. Most often the definition includes at least cadmium, lead, mercury and the radioactive metals. Metalloids (arsenic, polonium) may be included in the definition. Radioactive metals have both radiation toxicity and chemical toxicity. Metals in an oxidation state abnormal to the body may also become toxic: chromium(III) is an essential trace element, but chromium(VI) is a carcinogen. The toxicity of any metal depends on its ligands.
   Toxicity is a function of solubility. Insoluble compounds as well as the metallic forms often exhibit negligible toxicity. In some cases, organometallic forms, such as dimethyl mercury and tetraethyl lead, can be extremely toxic. In other cases, organometallic derivatives are less toxic such as cobaltocenium cation.
   Decontamination for toxic metals is different from organic toxins: because toxic metals are elements, they can't be destroyed. Toxic metals may be made insoluble or collected, possibly by the aid of chelating agents.
   Toxic metals can bioaccumulate in the body and in the food chain. The exceptions are barium and aluminum. Therefore, a common characteristic of toxic metals is the chronic nature of their toxicity.

Toxic metals

Aluminum has no biological role and its classification into toxic metals is controversial. Significant toxic effects and accumulation to tissues have been observed in renally impaired patients. However, individuals with healthy kidneys can be exposed to large amounts of aluminum with no ill effects. Thus, aluminum isn't considered dangerous to persons with normal elimination capacity.

Trace elements with toxicity

  • Chromium as hexavalent Cr(VI)
  • Nickel – nickel salts are carcinogenic
  • Copper
  • Ironiron poisoning

    Nonmetals

    Some heavy nonmetals may be erroneously called "metals", because they've some metallic properties.
  • Selenium – a nonmetal; essential element
  • Arsenic (see arsenic poisoning) is a metalloidFurther Information

    Get more info on 'Toxic Metal'.


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